Youth-GEMs 9th Science Café

Brief update about the 9th Science Café (August 21):

PhD researcher Winni Schalkwijk, who was invited to a previous Science Café, came back to recap some of the fundamentals of her work. Not only do our genes determine our mental health, also the environment and adaptive mechanisms (epigenetics) play an important role. A genome-wide association study (GWAS) is a research approach used to identify genomic variants that are statistically associated with a risk for a disease or a particular trait. In addition, Winni’s research also takes into account the exposome: the exposures (such as chronic stress) of an individual in a lifetime and how these relate to health. These all add to the outcomes and can accelerate or diminish our biological and epigenetic age. Winni looks into longitudinal data, from different international cohorts, and is aiming to gather scores to calculate genetic risk in relation to environmental factors.

Mariël Kanne visited our café in June and she came back with a recap as well about addressing ethical questions. People involved in the Youth-GEMs studies come from different cultures and have different values, experiences, knowledge, languages and have different gene-environment interactions. However, we have to be aware of the fact that all persons are (at the same time) different AND equal. We want to work in an ethical responsible manner. Oftentimes we learn more from questions than from answers. That’s why the input of young experts is key.


When young people are well-informed and have an understanding of the whole, they can feel empowered to make decisions. The conversation about genes for example underlines the importance of sharing knowledge and open access from an ethical perspective.  It’s empowering! Involvement is vital, as well as accessibility of information. The list of important values mentioned by the young experts from Euro Youth Mental Health is growing.

Find out more about Youth-GEMs here.